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Physics of the Cell
Cursusdoel
1) make quantitative statements about cellular processes
2) understand how discrete-state descriptions are connected to statistical mechanics
3) describe how forces affect molecules and their functions
4) classify different biological dynamics
5) know how chemo-mechanical coupling is fundamental for molecular and cellular dynamics
6) understand the concept of biophysical experimental setups
7) build computational models and solve them analytically or numerically
Vakinhoudelijk
- Physical models in cell biology
- Entropy and the Boltzman distribution
- Two-state systems and cooperative binding
- Random walks and the structure of macromolecules
- Mechanics of molecules and cellular structures
- Different modes of biological dynamics
- Polymerization dynamics
- Dynamics of molecular motors
Relation to research and professional field: Concepts and models from physics can help to understand the behaviour of molecules within cells. While most of the building blocks of living cells are well-known thanks to biochemical techniques, understanding how these molecules can establish long-range order and function far away from equilibrium often requires physical models. This course will enrich the student’s understanding of cell biology by teaching how the dynamics of cellular systems at different time and length scales emerges from.
Set up of the course:
The content is taught in two lectures per week. Assignments and/or computer practicals are discussed in one tutorial per week.
Relation to other courses:
This course builds upon the first-year course Biological Physics and has similar aims. Where the first year focused on very general principles, this course covers a number of more detailed topics.
This course is part of the profile Biophysics & Modeling and prepares you for level 3 courses linked to this profile and research groups linked to the master programme’s MCLS and Experimental Physics.
Entry requirements:
Successful completion of MBLS-101, MBLS-104, MBLS-106, MBLS-201. Preferably MBLS-108 (Prep4Physics).
Teaching format course (estimation):
Lectures = 40%
Tutorials = 20%
Assignment = 20%
Self study = 20%
Grading (see course manual for details):
Exam 1 (40%)
Exam 2 (40%)
Individual assignment(s) (20%)
Werkvormen
Werkcollege
Toetsing
Eindresultaat
Verplicht | Weging 100% | ECTS 7,5
Ingangseisen en voorkennis
Ingangseisen
Er is geen informatie over verplichte ingangseisen bekend.
Voorkennis
Er is geen informatie over benodigde voorkennis bekend.
Voertalen
- Engels
Cursusmomenten
Gerelateerde studies
Tentamens
Er is geen tentamenrooster beschikbaar voor deze cursus
Verplicht materiaal
Er is geen informatie over de verplichte literatuur bekend
Aanbevolen materiaal
Er is geen informatie over de aanbevolen literatuur bekend
Coördinator
dr. F.M. Berger | f.m.berger@uu.nl |
Docenten
dr. F.M. Berger | f.m.berger@uu.nl |
prof. dr. L.C. Kapitein | l.kapitein@uu.nl |
prof. dr. J. Lipfert | j.lipfert@uu.nl |
prof. dr. B.M. Mulder | b.m.mulder@uu.nl |
Inschrijving
Inschrijving
Van maandag 29 januari 2024 tot en met vrijdag 23 februari 2024
Na-inschrijving
Van dinsdag 2 april 2024 tot en met woensdag 3 april 2024
Inschrijving niet geopend
Permanente link naar de cursuspagina
Laat in de Cursus-Catalogus zien