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Immunology and Infectious Diseases (2023/2024: Semester 2 – Spring)
Cursusdoel
After completing this course students are able to:
- describe the main processes in immunology and replication of pathogens.
- link clinical signs to molecular pathogenesis.
- read recent primary research papers and judge the validity of arguments and conclusions in these papers.
- formulate a research project.
- discuss the integration of different biomedical aspects within a specific theme of interest.
Vakinhoudelijk
Content
Infectious diseases and disorders of immunity are continuous threats to the lives and wellbeing of humans. Studying fundamental processes of immunology such as the recognition of antigen, development of mature lymphocyte receptor repertoires, and adaptive immune response is crucial for understanding how the human body deals with the invasion of microorganisms on a daily basis. Thus, the first part of this course examines infectious disease-oriented problems related to the function and biology of microorganisms, molecular pathogenesis of infections, microbial virulence and therapy resistance, interactions between host and microorganisms, and inflammation and tissue damage. Then, we will switch to clinical immunology where the immune system is either not (entirely) functional or deregulated. Well-known examples are hypersensitivities e.g. allergies, autoimmune diseases, and immune deficiencies like AIDS.
The second part of the course focusses on a research grant application written in group work. The academic skills of writing, reviewing and presenting are developed while students are dealing consecutively with three different topics (e.g. tumorimmunology, vaccines, antigen-presentation).
Infectious diseases and disorders of immunity are continuous threats to the lives and wellbeing of humans. Studying fundamental processes of immunology such as the recognition of antigen, development of mature lymphocyte receptor repertoires, and adaptive immune response is crucial for understanding how the human body deals with the invasion of microorganisms on a daily basis. Thus, the first part of this course examines infectious disease-oriented problems related to the function and biology of microorganisms, molecular pathogenesis of infections, microbial virulence and therapy resistance, interactions between host and microorganisms, and inflammation and tissue damage. Then, we will switch to clinical immunology where the immune system is either not (entirely) functional or deregulated. Well-known examples are hypersensitivities e.g. allergies, autoimmune diseases, and immune deficiencies like AIDS.
The second part of the course focusses on a research grant application written in group work. The academic skills of writing, reviewing and presenting are developed while students are dealing consecutively with three different topics (e.g. tumorimmunology, vaccines, antigen-presentation).
Format
Introductions, presentations and group discussions take place during class. In addition to attending class, students study the basic principles in immunology and infection guided by lectures, questions and readings. The second part of the course consists of project work in small groups formulating a grant application, critically reviewing the application of another group and presenting a third one at a symposium Some of the activities will need to be given in a hybrid or online form due to the current situation.
Introductions, presentations and group discussions take place during class. In addition to attending class, students study the basic principles in immunology and infection guided by lectures, questions and readings. The second part of the course consists of project work in small groups formulating a grant application, critically reviewing the application of another group and presenting a third one at a symposium Some of the activities will need to be given in a hybrid or online form due to the current situation.
Werkvormen
UCU sci 3 course
Toetsing
class participation
Verplicht | Weging 20% | ECTS 1,5
grant application (review)
Verplicht | Weging 10% | ECTS 0,75
grant application (symposium)
Verplicht | Weging 10% | ECTS 0,75
grant application (proposal)
Verplicht | Weging 20% | ECTS 1,5
*midterm FEEDBACK*
Niet verplicht
written exam
Verplicht | Weging 30% | ECTS 2,25
oral presentation
Verplicht | Weging 10% | ECTS 0,75
Ingangseisen en voorkennis
Ingangseisen
Er moet voldaan zijn aan de cursussen:
Voorkennis
Er is geen informatie over benodigde voorkennis bekend.
Voertalen
- Engels
Cursusmomenten
Gerelateerde studies
Tentamens
Er is geen tentamenrooster beschikbaar voor deze cursus
Verplicht materiaal
-
BOEKAbbas AK, Lichtman AH, Pillai S. Basic Immunology : Functions and Disorders of the Immune System. Seventh ed. Philadelphia, PA: Elsevier; 2023. e-book available via UBU https://www.clinicalkey.com/dura/browse/bookChapter/3-s2.0-C20210033009.
-
BOEKMedical Microbiology Patrick R. Murray, Ken S. Rosenthal and Michael A. Pfaller. 9th edition, 2021, Elsevier; ISBN: 9780323673228 e-book available via Elsevier e-book from UBU
Aanbevolen materiaal
Er is geen informatie over de aanbevolen literatuur bekend
Coördinator
| dr. K.D. Denzer | k.denzer@umcutrecht.nl |
Docenten
| dr. K.D. Denzer | k.denzer@umcutrecht.nl |
Inschrijving
Let op: deze cursus is niet toegankelijk voor studenten van andere faculteiten, bijvakkers mogen zich dus niet inschrijven.
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