Uw huidige browser heeft updates nodig. Zolang u niet update zullen bepaalde functionaliteiten op de website niet beschikbaar zijn.
Let op: het geselecteerde rooster heeft overlappende bijeenkomsten.
Volgens onze gegevens heb je nog geen vakken behaald.
Je planning is nog niet opgeslagen
Let op! Uw planning heeft vakken in dezelfde periode met overlappend timeslot
Pharmacology
Cursusdoel
After completing this course students are able to:
In this course, the final course grade is based on three elements: two written exams and an essay. Learning goals 1-4 are incorporated in all assessment elements.
- explain the efficacy of existing drug therapies in a rational way in terms of molecular targets, cellular actions, and physiological consequences of pharmacological treatment.
- suggest targets for drug development of diseases on the basis of pathophysiological insights.
- apply pharmacological models in the description of concentration-response, time-concentration, and time-response relationships of drugs.
- discuss how the development and use of drugs requires a multidisciplinary approach.
- engage in collaborative learning and demonstrate effective communication skills.
In this course, the final course grade is based on three elements: two written exams and an essay. Learning goals 1-4 are incorporated in all assessment elements.
- Written exam Pharmacodynamics (40%): you should be able to demonstrate qualitative and quantitative understanding of models of drug-receptor interaction
- Written exam Pharmacokinetics (40%): you should be able to demonstrate qualitative and quantitative understanding of the kinetics of drugs in the human body
- Essay (20%): you should be able to demonstrate understanding of the scientific discipline of pharmacology, its place in drug research and in health care, and its connections to other life sciences disciplines
Vakinhoudelijk
The functioning of the (diseased) human body can be affected by medicines, which act through a variety of molecular mechanisms. This course illustrates the various ways of drug action through an in-depth study of a drug, a disease or pharmacological principle (to be determined). These three approaches have been chosen because they demonstrate drug effects at a variety of the organizational levels (molecule, cell, whole organism) of animals and man. We also review the recent advances in rational drug design.
Although the course only treats limited amount of diseases, it highlights the underlying physiological and pharmacological principles of rational drug use and development. It stresses the importance of neuronal/hormonal (whole body) and biochemical regulation (whole cell) for proper physiological and cellular functioning, as well as homeostatic control and dysfunction during pathological processes. The identification of potential drug targets and the interaction of drugs with macromolecules (enzymes, cell surface receptors, signaling molecules) as a main pharmacological principle is another topic central to our study, and one that requires quantitative pharmacological and statistical methods.
Format
During the course, students are required to learn the basic pharmacological models that describe concentration-response, time-concentration, and time-response relationships of drugs by using available literature and several simulation applications. They may refer to spreadsheet programs and course lectures for assistance.
Although the course only treats limited amount of diseases, it highlights the underlying physiological and pharmacological principles of rational drug use and development. It stresses the importance of neuronal/hormonal (whole body) and biochemical regulation (whole cell) for proper physiological and cellular functioning, as well as homeostatic control and dysfunction during pathological processes. The identification of potential drug targets and the interaction of drugs with macromolecules (enzymes, cell surface receptors, signaling molecules) as a main pharmacological principle is another topic central to our study, and one that requires quantitative pharmacological and statistical methods.
Format
During the course, students are required to learn the basic pharmacological models that describe concentration-response, time-concentration, and time-response relationships of drugs by using available literature and several simulation applications. They may refer to spreadsheet programs and course lectures for assistance.
Werkvormen
UCU SCI 3 course
Toetsing
Essay
Verplicht | Weging 20% | ECTS 1,5
*midterm FEEDBACK*
Niet verplicht
exam Pharmacodynamics
Verplicht | Weging 40% | ECTS 3
exam Pharmacokinetics
Verplicht | Weging 40% | ECTS 3
Ingangseisen en voorkennis
Ingangseisen
Er moet voldaan zijn aan de cursussen:
Voorkennis
Er is geen informatie over benodigde voorkennis bekend.
Voertalen
- Engels
Cursusmomenten
Gerelateerde studies
Tentamens
Er is geen tentamenrooster beschikbaar voor deze cursus
Verplicht materiaal
| Materiaal | Omschrijving |
|---|---|
| BOEK | Rang & Dale’s Pharmacology by JM Ritter et al. 9th edition (2020). ISBN 978-0-7020-7448-6 This book is also made available online by the Utrecht University Library. |
| BOEK | Introduction to drug disposition and pharmacokinetics by SH Curry & R Whelpton (2017) EAN 9781119261049 This book is also made available online by the Utrecht University Library |
Aanbevolen materiaal
| Materiaal | Omschrijving |
|---|---|
| DIVERSE | Other (parts of) books and review articles will be recommended during the course |
Coördinator
| prof. dr. G.M.H. Engels | G.M.H.Engels@uu.nl |
Docenten
| prof. dr. G.M.H. Engels | G.M.H.Engels@uu.nl |
Inschrijving
Let op: deze cursus is niet toegankelijk voor studenten van andere faculteiten, bijvakkers mogen zich dus niet inschrijven.
Naar OSIRIS-inschrijvingen
Permanente link naar de cursuspagina
Laat in de Cursus-Catalogus zien
klikt, stop je een vak in je rugzak, zodat je dit vak door de rest van de CursusPlanner mee kunt nemen.