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Research Design and Analysis; moleculair en cel (2025/2026: periode 3)
Cursusdoel
Learning objectives
By the end of this course, you should be able to:
• compare critically the advantages and limitations of different techniques, specific to an experimental project
• design an experiment to answer a self-formulated research question
• process raw data into clear tables and figures supported with statistical considerations, by using spreadsheet programs
• formulate new insights and hypotheses by interpreting data
• apply the best practices to uphold scientific integrity in your work
• communicate clearly your research and its context to fellow scientists and the general public, both orally and in writing
• provide constructive feedback to peers on their design, research results and manuscript
• improve your own work by critically implementing feedback
By the end of this course, you should be able to:
• compare critically the advantages and limitations of different techniques, specific to an experimental project
• design an experiment to answer a self-formulated research question
• process raw data into clear tables and figures supported with statistical considerations, by using spreadsheet programs
• formulate new insights and hypotheses by interpreting data
• apply the best practices to uphold scientific integrity in your work
• communicate clearly your research and its context to fellow scientists and the general public, both orally and in writing
• provide constructive feedback to peers on their design, research results and manuscript
• improve your own work by critically implementing feedback
| Skills | Part of the course | Explicitely assessed? |
| Writing | v | v |
| Oral presentation | v | v |
| Dealing with data | v | v |
| Practical research skills | ||
| Research skills | v | v |
| Group work | v | v |
| Critical thinking | v | v |
| Carrier orientation | ||
| Interdisciplinarity |
Vakinhoudelijk
Entry requirements
For the Biology bachelor: the "Molecular Genetic Research Techniques" (MGOT) and "The Cell" courses are mandatory. The courses "Metabolism and Biochemistry" and "Cells and Tissues" (level 3) are recommended.
For the MBLS bachelor: the "Molecular Biology & Biochemical Techniques" (MBBT) course is mandatory. The course "Genomes, Cells & Tissues" is recommended.
The course is open to ‘advanced’ second year students, but students in their third year will have priority.
Study area of interest
The Research Design and Analysis course (B-B3RDA21) fits the Cell Biology and Neurobiology study area and is a fully-fledged theoretical alternative to Molecular Cell Research.
Content
The Research Design and Analysis (B-B3RDA21) course has a molecular and cellular focus and is a fully-fledged theoretical alternative to Molecular Cell Research.
In this course, students go through the research cycle with special attention to setting up and justifying experiments, processing research results and providing feedback. Projects and (raw) data are offered from various molecular and cellular research disciplines, as they are also available in an open research culture (open science). The students are introduced to the usefulness and importance of an open research culture.
At the beginning of the course, students receive a case. Inspired by this case, students work in small groups (3-4 students) to formulate a problem statement, research question and hypothesis and draw up a detailed research plan. The research plan is provided with (peer) feedback and after the research plan has been approved, students are given access to the raw data of an experiment that (partially) corresponds to the experiments described in the research plan. The students will process and interpret the raw data themselves and translate it into clear tables, figures and conclusions. The results are presented to the researcher and fellow students and reported in the form of a scientific article. Just as in an open research culture, in this course it is important to organize and translate the results so that they are accessible and understandable to the public.
Forms of education
The course consists of the online learning environment (Brightspace) in addition to the weekly progress meetings (with the project supervisor) and the joint group meetings (whole class, with the coordinator), and some seminars. Attendance is compulsory to all meetings unless properly justified.
Assessment
The final grade is calculated as following:
• Participation, collaboration and commitment (25%, individual assessment)
• Individual presentation throughout the course (15%, individual assessment)
• Written scientific report (50%, group assessment)
• Final group presentation (10%, group assessment)
For each component, grades are evaluated according to pre-determined rubrics.
The course is considered completed satisfactorily if the final grade is sufficient (5.5 or higher). As each component is mandatory, failing one or more components causes failing the course.
For the Biology bachelor: the "Molecular Genetic Research Techniques" (MGOT) and "The Cell" courses are mandatory. The courses "Metabolism and Biochemistry" and "Cells and Tissues" (level 3) are recommended.
For the MBLS bachelor: the "Molecular Biology & Biochemical Techniques" (MBBT) course is mandatory. The course "Genomes, Cells & Tissues" is recommended.
The course is open to ‘advanced’ second year students, but students in their third year will have priority.
Study area of interest
The Research Design and Analysis course (B-B3RDA21) fits the Cell Biology and Neurobiology study area and is a fully-fledged theoretical alternative to Molecular Cell Research.
Content
The Research Design and Analysis (B-B3RDA21) course has a molecular and cellular focus and is a fully-fledged theoretical alternative to Molecular Cell Research.
In this course, students go through the research cycle with special attention to setting up and justifying experiments, processing research results and providing feedback. Projects and (raw) data are offered from various molecular and cellular research disciplines, as they are also available in an open research culture (open science). The students are introduced to the usefulness and importance of an open research culture.
At the beginning of the course, students receive a case. Inspired by this case, students work in small groups (3-4 students) to formulate a problem statement, research question and hypothesis and draw up a detailed research plan. The research plan is provided with (peer) feedback and after the research plan has been approved, students are given access to the raw data of an experiment that (partially) corresponds to the experiments described in the research plan. The students will process and interpret the raw data themselves and translate it into clear tables, figures and conclusions. The results are presented to the researcher and fellow students and reported in the form of a scientific article. Just as in an open research culture, in this course it is important to organize and translate the results so that they are accessible and understandable to the public.
Forms of education
The course consists of the online learning environment (Brightspace) in addition to the weekly progress meetings (with the project supervisor) and the joint group meetings (whole class, with the coordinator), and some seminars. Attendance is compulsory to all meetings unless properly justified.
Assessment
The final grade is calculated as following:
• Participation, collaboration and commitment (25%, individual assessment)
• Individual presentation throughout the course (15%, individual assessment)
• Written scientific report (50%, group assessment)
• Final group presentation (10%, group assessment)
For each component, grades are evaluated according to pre-determined rubrics.
The course is considered completed satisfactorily if the final grade is sufficient (5.5 or higher). As each component is mandatory, failing one or more components causes failing the course.
Werkvormen
Groepsonderwijs
Hoorcollege
Werkcollege
Hoorcollege
Werkcollege
Toetsing
Eindresultaat
Verplicht | Weging 100% | ECTS 7,5
Ingangseisen en voorkennis
Ingangseisen
Je moet inschreven staan voor een van de volgende opleidingen:
- Molecular and Biophysical Life Sciences
- Biologie
- Scheikunde
Voorkennis
For the Biology bachelor: the "Molecular Genetic Research Techniques" (MGOT) and "The Cell" courses are mandatory. The courses "Metabolism and Biochemistry" and "Cells and Tissues" (level 3) are recommended. For the MBLS bachelor: the "Molecular Biology & Biochemical Techniques" (MBBT) course is mandatory. The course "Genomes, Cells & Tissues" is recommended. The course is open to ‘advanced’ second year students, but students in their third year will have priority.
Voertalen
- Engels
Cursusmomenten
Tentamens
Er is geen tentamenrooster beschikbaar voor deze cursus
Verplicht materiaal
Er is geen informatie over de verplichte literatuur bekend
Aanbevolen materiaal
Er is geen informatie over de aanbevolen literatuur bekend
Opmerkingen
2x24 personen
Coördinator
| dr. A.E.D. Chaigne | a.e.d.chaigne@uu.nl |
Docenten
| M. Locarno MSc | m.locarno@uu.nl |
| dr. M. Harterink | M.Harterink@uu.nl |
Inschrijving
Let op: deze cursus is niet toegankelijk voor studenten van andere faculteiten, bijvakkers mogen zich dus niet inschrijven.
Inschrijving
Van maandag 3 november 2025 tot en met vrijdag 21 november 2025
Na-inschrijving
Van maandag 19 januari 2026 tot en met dinsdag 20 januari 2026
Inschrijving niet geopend
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